“Although we are engineers, we do know the medical problems that clinicians face,” Lin said. Its strength rests in part on its close collaboration with clinicians. The lab took devices that were stationary and portable and made them stretchable and wearable, driving a transformation across the landscape of healthcare monitoring. Thanks to technological advances and the hard work of clinicians over the last few decades, ultrasound has received an ongoing wave of interest, and the Xu lab is often mentioned in the first breath as an early and enduring leader in the field, particularly in wearable ultrasound. The ultrasonic system-on-patch also represents a breakthrough in the development of the Internet of Medical Things (IoMT), a term for a network of medical devices connected to the internet, wirelessly transmitting physiological signals into the cloud for computing, analysis and professional diagnosis. For healthy populations, our device can measure cardiovascular responses to exercise in real time and thus provide insights into the actual workout intensity exerted by each person, which can guide the formulation of personalized training plans.” Abnormal values of blood pressure and cardiac output, at rest or during exercise, are hallmarks of heart failure. “The sensor can evaluate cardiovascular function in motion. “This technology has lots of potential to save and improve lives,” Lin said. A machine learning component helps interpret the data and track subjects in motion.Īccording to the lab’s findings, the ultrasonic system-on-patch allows continuous tracking of physiological signals from tissues as deep as 164 mm, continuously measuring central blood pressure, heart rate, cardiac output, and other physiological signals for up to twelve hours at a time. In this work, it includes a small, flexible control circuit that communicates with an ultrasound transducer array to collect and transmit data wirelessly. However, previous soft ultrasonic sensors all require tethering cables for data and power transmission, which largely constrains the user’s mobility. This fully integrated autonomous wearable ultrasonic system-on-patch (USoP) builds on the lab’s previous work in soft ultrasonic sensor design. The research emerges from the lab of Sheng Xu, a professor of nanoengineering at UC San Diego Jacobs School of Engineering and corresponding author of the study. “We made a truly wearable device that can sense deep tissue vital signs wirelessly.” candidate in the Department of Nanoengineering at UC San Diego and the first author on the study. “This project gives a complete solution to wearable ultrasound technology-not only the wearable sensor, but also the control electronics are made in wearable form factors,” said Muyang Lin, a Ph.D. The paper, “A fully integrated wearable ultrasound system to monitor deep tissues in moving subjects,” is published in the issue of Nature Biotechnology. It facilitates potentially life-saving cardiovascular monitoring and marks a major breakthrough for one of the world’s leading wearable ultrasound labs. A team of engineers at the University of California San Diego has developed the first fully integrated wearable ultrasound system for deep-tissue monitoring, including for subjects on the go.
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